The ChEMBL-og

The Kinase SARfari interface has been updated and is now using the JME Molecular Editor for compound drawing and editing. JME is an easy to use fast loading applet, for more information visit: http://www.molinspiration.com/jme/

When I started work, if you wanted to tell someone something, you wrote a handwritten note, posted it internally to a typing pool, told them how many copies you wanted, and a few days later things would turn up in the internal post. To distribute things further, you had to then fill envelopes, lick stamps and then post them. (For the youth reading this, Google any of the unfamiliar words/phrases). It was incredible that anything got done at all (penicillin, the transistor, gps, etc it really is. We live in different times, and as a group we communicate in three general ways to the world. The ChEMBL-og chembl.blogspot.com - this blog! Mostly news of broad interest, some ephemera, some recruitment, and some analyses of data, new drug approval news, interesting papers, conferences, book and hotel reviews for scientists, etc. The Group homepage at www.ebi.ac.uk/chembl - links to the online resources (currently kinase sarfari and chembldb are live). The ChEMBL twitter feed www...

The initial web front-end to the ChEMBL SAR data is now available on the EMBL-EBI website, as are data downloads in MySQL and a variety of Oracle format downloads. The web interface is at http://www.ebi.ac.uk/chembldb/index.php The database downloads are at ftp://ftp.ebi.ac.uk/pub/databases/chembl/chembl_01/ We'll add some front-end documentation in the near future, and also restart the schema walkthrough web meetings, so if you are interested in these, please sign up to the chembl-announce mailing list , or configure an RSS feed on the blog . The picture above is the unbelievable ' King of Herrings ', a charmingly named and only occasionally encountered deep sea oarfish, it is the world's longest bony fish you know...

We have a new position available within the ChEMBL group from January 2010 onwards - the role is for someone to do data integration, analysis, and work-flow prototyping for chemogenomics/bioassay data. The post should be advertised on the EMBL recruitment website soon, there are also several other excellent jobs listed at EMBL-EBI.

Registration for TACBAC 2010 is now open - TACBAC stands for Therapeutic Applications of Computational Biology and Chemistry. Details on the conference can be found here

The deadline for application for bursaries for the small molecule bioactivity course at the EMBL-EBI is approaching - Friday November 6th. If you wish to attend for free (or at a really discounted rate) please consider applying now. We are starting to assemble the material for the course now, and have secured some truly outstanding external speakers - it should be good!

There is, what looks like, an excellent meeting in London, full details are on the SMR website . I hope I feel better by then. SMR Award Meeting: Recent Disclosures of Clinical Candidates 10th December 2009   National Heart & Lung Institute, Kensington, London Programme : 09.30 Registration and coffee 10.0 0 SMR Award lecture: The Discovery and development of Januvia ™ ,   Dr. Ann Weber ,  Merck (Introduction by -  Rob Williams,  Cancer Research UK ) Session 1 - Chair: Mark Searcy,  University of East Anglia 11.00    Chris Murray,  Astex From fragment to clinic - the discovery of the hsp90 inhibitor, AT13387. 11.45 George Muller,  Celgene The discovery of apremilast. 12.30 Lunch (Including SMR AGM 13.10-13.30) Session 2 - Chair:  Diane Coe,  GSK 13.30 David Fox,  Pfizer The discovery of a second generation long-acting PDE5 inhibitor. 14.15 Simon Hodgson,  GSK T he di...