The ChEMBL-og

Image generated using DALLE-3 Introduction Dear ChEBI users, If you have visited the ChEBI website recently, you have been able to intuit that something really great is just about to come. Our team has been working for the last three years on the redevelopment of ChEBI , which includes: a new website, modern infrastructure, a new submission and curator tool and improvements in the ChEBI data products (ontology, TSV flat files, SDF files, database dump). Many things to cover in one single post, for that reason, this is one in a series of blog posts describing ChEBI 2.0. Today, we are going to take a look at the ChEBI data products enhancements. What is new? We are going to describe the changes according to the type of product, starting with one of our most widely used data products: the ChEBI Ontology. ChEBI Ontology These are the changes we have implemented: Homogenized prefixes We decided to homogenise the ChEBI prefixes. In the past, we used to have http://purl.obolibrary.org/obo/ch...

The Chemical Biology Services team invites applications for a 3-year ARISE2 Postdoctoral Fellowship – a unique postdoctoral opportunity that combines advanced research training with hands-on experience in developing innovative technologies and methods to enhance scientific services. Why apply? Make an Impact: Collaborate on high-impact projects that will directly shape and improve the scientific services we provide. Tailored to You: Each fellowship project is developed in collaboration with the fellow and the host team – possibly even involving an industry partner – to ensure a project that combines your ideas with the vision of of the host. Prepare for the Future: The ARISE2 Fellowship is designed to prepare fellows for dynamic careers within research infrastructures, providing both technical depth and professional development. If this sounds interesting, please get in touch by the end of August at oboyle@ebi.ac.uk with your CV. Note that we recruit worldwide. Here is a ...

We are delighted to announce that ChEBI’s beta version is now out and can be accessed at: https://www.ebi.ac.uk/chebi/beta/ As many of you know, ChEBI is a widely used database and ontology of chemical entities of biological interest. It has a growing user base numbered in the hundreds of thousands and with millions of accesses each year. ChEBI has for the past >20 years provided the biological community with access to definitive small molecule information and data, including accurate representations of often complex chemical structures. Additionally, ChEBI is used widely as a reference database and ontology by many important bioinformatics resources such as Rhea, MetaboLights, UniProt, GO, IEDB, Reactome, amongst others. ChEBI is, thus, a fundamental and core component of the global bioscience infrastructure. Outdated infrastructure  Back in 2021, ChEBI's software infrastructure was increasingly fragile. ChEBI's current software code base dates back to its creation in the e...