The ChEMBL-og

The following is written in Japanese.... ケンブルチーム(ChEMBL Team)は、欧州バイオインフォマティクス研究所( EMBL-EBI )にあり、創薬研究に有用な化合物やターゲット情報を提供するデータベースを開発しています。 ChEMBLdb は、創薬研究に有用な医薬品化合物の情報を提供するデータベースです。現在、約50万個の化合物情報、約190万件の活性情報及びそれらのターゲット情報が登録されています。ユーザーは、生物活性化合物の情報を部分構造検索や類似性検索で調査したり、また、ターゲットのアミノ酸配列からBLAST検索でアッセイ情報を収集することができます。 ケンブルチームでは、キナーゼに特化したカイネースサファリ( Kinase SARfari )のサービスも開始しました。 日本語でのご質問、ご要望は kaz(at)ebi.ac.uk までどうぞ。チームメンバー一同、皆さんのご利用をお待ちしています！

On Friday July 10th we plan to hold a further Druggability Workshop for the EMBL-EBI Industry Partners. If anyone is interested in participating in this highly interactive and participatory workshop AND also interested in joining the Industry Partner program; please contact me.....

The ChEMBL caravan will always have a place in our hearts, but now we have an office, and we must move on from the pain. It has some walls and a door, with a nice hook for jackets and coats. It is nice, bijou even, and has bought a smile to all our faces. Most importantly it gives us a place to entertain guests and visitors, so if anyone is in the area, please pop by and have a cup 'o tea and a slice 'o cake. As a sideline, to fund the tea and cakes, we have a nice T-shirt - XXXL only, minimum order 10 pieces if you are interested.

I have provisionally planned the ChEMBL group retreat for 2009. It will be in Crieff, Scotland , and will be in late September. The format will allow detailed discussion and brainstorming of ideas for the ChEMBL project, and will be themed around the following areas. Open-Source Drug Discovery and Open Science. Patent data-mining and indexing. Auto-curation and in-line predictive model generation. An Ontology for drug discovery screening cascades. A web-services primer. The mornings and evenings will be informal discussions of science, while the afternoons will be fun, fungi, flora and photography (who said alliteration is dead!) oriented walks in the wooded areas around Crieff. The picture above is of a reasonably rare parasite of truffles (a Cordyceps sp. ) found in Crieff around the same time of year in 2008. This is the fruiting stage of the fungus (the teleomorph), the non-fruiting body stage (the anamorph) of a closely related fungus is the source of the powerful immunosupp...

I thought I would post a note on the EMBL-EBI's Industry Programme . This is a forum open to all life-science companies to network and understand the tools, resources and direction of the EMBL-EBIs activities, and also encourage discussion of pre-competitive and collaborative activities between life-science companies. Given the increasing demands for cost-reduction, data integration and knowledge representation within the sector this activity is becoming increasingly important. Details of how to join the can be found on the EMBL-EBI web-site (link above). An analogous group exists for smaller companies (SME/SMBs).