The theme of the book is around The Neutral Theory, quite a contentious issue in evolution (essentially, this states that the vast majority of observed mutations at a molecular level are not adaptive; now flame me!) This book changed the way I thought about mutation, protein sequence and structure and function. Forever.
%T Population Genetics, Molecular Evolution, and The Neutral Theory %A Motoo Kimura %E J.F. Crow %D 1994 %I Chicago %O ISBN: 0-226-43562-8