Protein Ligand Affinity Databases

I came across a nice tabular summary of some existing 'public' 'primary' protein-ligand interaction databases that primarily focus on protein-ligand affinity data (so Ki, Kd, IC50, EC50, etc.), that I have reproduced below (many thanks to Helena Strömbergsson, from Uppsala University for the data).

Name	Target Class Focus	Approx size
BindingDB	All	~48,000
PDSP	Receptors	~47,000
BRENDA	Enzymes	~19,000
BindingMOAD	All	~3,500
PDBBind	All	~3,500
AffinDB	All	~700
PLD	All	~500

The comparable number from StARlite (31) are 507,645 (of which 186,370 are better than 100nM) for affinity class end-points. Oh, and we have started a new load.....

Comments

Unknown said…

This shows how putting this data in the public sector will be a huge boon for scientific researchers! It will also lead many to say "I want that! When can I get it?!" :-)

Keep up the great work!

18 March 2009 at 12:47

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