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Monday, 17 February 2014

USANS - February 2014

Just catching up on some recently published USAN statements.

USAN Research Code InChIKey (Parent) Drug Class Therapeutic class Target
asvasiran-sodium

ALN-RSV01

n/a RNAi therapeutic n/a
beclabuvir

BMS-791325

ZTTKEBYSXUCBSE-VSBZUFFNSA-N synthetic small molecule therapeutic HCV NS5B polymerase
benzhydrocodonebenzhydrocodone-hydrochloride
KP-201
VPMRSLWWUXNYRY-PJCFOSJUSA-N natural product derived small molecule therapeutic Opioid receptors
bradaniclinebradanicline-hydrochloride

TC-5619

OXKRFEWMSWPKKV-GHTZIAJQSA-N synthetic small molecule therapeutic alpha-7 nicotinic acetylcholine receptor
briciclibbriciclib-sodium

ON-014185

LXENKEWVEVKKGV-BQYQJAHWSA-N synthetic small molecule therapeutic n/a
ceritinib

NVP-LDK378-NX

VERWOWGGCGHDQE-UHFFFAOYSA-N synthetic small molecule therapeutic ALK
dasabuvir

ABT-333

NBRBXGKOEOGLOI-UHFFFAOYSA-N synthetic small molecule therapeutic HCV NS5B polymerase

defactinibdefactinib-hydrochloride

VS-6063

FWLMVFUGMHIOAA-UHFFFAOYSA-N synthetic small molecule therapeutic FAK
dianhydrogalactitol

VAL-083, NSC-1323313

AAFJXZWCNVJTMK-UHFFFAOYSA-N synthetic small molecule therapeutic DNA
dinutuximab
n/a
n/a monoclonal antibody therapeutic GD2
diridavumab

CR-6261

n/a monoclonal antibody therapeutic haemagglutinin
enceniclineencenicline-hydrochloride

EVP-6124

SSRDSYXGYPJKRR-ZDUSSCGKSA-N synthetic small molecule therapeutic alpha-7 nicotinic acetylcholine receptor
esuberaprostesuberaprost-sodium


APS-314d, BPS-314d

CTPOHARTNNSRSR-NOQAJONNSA-N synthetic small molecule therapeutic IP1 receptor
filociclovir


MBX-400

KMUNHOKTIVSFRA-KXFIGUGUSA-N synthetic small molecule therapeutic CMV DNA polymerase
fosdagrocorat

PF-04171327

n/a synthetic small molecule therapeutic GR
gedatolisib

PF-05212384, PKI-587

DWZAEMINVBZMHQ-UHFFFAOYSA-N synthetic small molecule therapeutic PI3K & mTOR
glasdegib

PF-04449913

SFNSLLSYNZWZQG-VQIMIIECSA-N synthetic small molecule therapeutic smoothened
indoximod
D-1MT
n/a natural product derived small molecule therapeutic IDO
latiglutenase

ALV-003

n/a enzyme therapeutic n/a
lulizumab-pegol BMS-931699

n/a monoclonal antibody therapeutic CD28
ombitasvir

ABT-267

PIDFDZJZLOTZTM-KHVQSSSXSA-N synthetic small molecule therapeutic HCV NS5a
omega-3-carboxylic-acids
n/a
n/a natural product derived small molecule therapeutic n/a
peficitinib

ASP-015K

DREIJXJRTLTGJC-UHFFFAOYSA-N synthetic small molecule therapeutic JAK
pegargiminase
n/a
n/a enzyme therapeutic n/a
pembrolizumab
n/a
n/a monoclonal antibody therapeutic Programmed cell death 1 (PDCD1)
polmacoxib

CG-100649

IJWPAFMIFNSIGD-UHFFFAOYSA-N synthetic small molecule therapeutic COX-2
sarolaner

PF-6450567

FLEFKKUZMDEUIP-QFIPXVFZSA-N synthetic small molecule therapeutic n/a
transcrocetinate-sodium
n/a
n/a natural product derived small molecule radiation sensitizer n/a
uprosertib

GSK-2141795C

AXTAPYRUEKNRBA-JTQLQIEISA-N synthetic small molecule therapeutic AKT1
venetoclax

ABT-199

LQBVNQSMGBZMKD-UHFFFAOYSA-N synthetic small molecule therapeutic BCL-2

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