As promised in our earlier post , here are some more details on making the most of the new ChEMBL web services. The best place to get started is to head over to the documentation page: https://www.ebi.ac.uk/chembl/api/data/docs . There you will find the list of resources (e.g. Molecule, Target and Assay) that are available and their methods. More importantly you can also execute each method with your own or default parameters, and view the URL, the response content and response status code. This is definitely the quickest way to start familiarizing yourself with the new ChEMBL web services. Looking at the resources in more detail, you will find that each resource has three basic methods: 1. https://www.ebi.ac.uk/chembl/api/data/RESOURCE - will return all available objects of type RESOURCE from ChEMBL. An example could be https://www.ebi.ac.uk/chembl/api/data/molecule which returns all molecules (remember that data is paginated - more on this later). 2. https://www.ebi.ac.