Skip to main content

Join the ChEMBL Team!



We are looking for talented individuals to help us maintain and develop the ChEMBL and SureChEMBL resources and currently have a number of open positions within the team. If you are looking for an exciting new role and would like to work with us on the beautiful Wellcome Genome Campus, here are details of the positions:

Data Integration Scientist


We are looking for a Scientist with a passion for data integration to manage the incorporation of drug discovery data into the ChEMBL database.

Responsibilities will include:
  • Responsibility for the handling, processing and integration of data into the ChEMBL database.
  • Facilitating the deposition of datasets directly into ChEMBL through working with external collaborators.
  • Applying text- & data-mining techniques for the development of effective large-scale curation strategies.
  • Developing methods for the application and maintenance of ontologies in ChEMBL.
  • Working with other teams to facilitate the integration of data between different EBI resources.

Essential requirements include:
  • A BSc (or equivalent) in a life-science subject (e.g. biological or biomedical sciences).
  • 3+ years of postgraduate experience in scientific application development, database development or text- & data-mining, with a demonstrable track record of achievement.
  • Proficient in at least one programming/scripting language (Python knowledge is highly desirable).
  • Good knowledge of relational databases, data modelling, SQL and PL/SQL, and RESTful web-services.
  • Experience in integrating diverse data sets.

For full details and to apply for the position, please visit the EMBL website:
https://www.embl.de/jobs/searchjobs/index.php?ref=EBI_01173&newlang=1&loc%5B%5D=2


Software Engineer - Dev Ops


We are seeking a talented Software Engineer/Dev Ops Developer to work on SureChEMBL, one of the largest live resources of chemistry extracted from patent data.

Responsibilities will include:
  • Maintaining and improving the SureChEMBL system;
  • Building new monitoring tools and dashboards;
  • Developing new functionalities in collaboration with colleagues and collaborators;
  • Profiling and scaling the cloud-based IaaS patent processing pipeline;
  • Optimizing the application stack for maximum speed and scalability;

Essential requirements include:
  • A minimum of 3 years of professional development experience;
  • Strong core Java Enterprise Edition development skills and understanding of Java design principles;
  • Experience of defining and creating Continuous Integration and Development environments using technologies such as Jenkins, Maven, Artifactory;
  • A solid understanding of the Open Stack platform;
  • Experience with distributed queue messaging (e.g. Amazon SQS, RabbitMQ)
  • Experience with relational databases (mySQL, PostgreSQL);
  • A solid foundation in computer science, with strong competencies in concurrency, shell scripting, and software design;

For full details and to apply for the position, please visit the EMBL website:
https://www.embl.de/jobs/searchjobs/index.php?ref=EBI_01163&newlang=1&loc%5B%5D=2


Software Engineer - Web Developer


We require a passionate Web Developer who can design and develop robust solutions that deliver ChEMBL data to our extensive user community.

Responsibilities will include:
  • Developing web-based solutions to better deliver ChEMBL resources to users
  • Maintaining and further developing the infrastructure that supports interfaces on chemogenomics data
  • Working with other members of the team, collaborators and users to develop and deliver new and innovative ways to analyse and visualise ChEMBL data
  • Integrating chemogenomics data with that from other relevant resources at the EBI and beyond
  • Keeping up-to-date with relevant developments in the field of web development

Essential requirements include:
  • A BSc (or equivalent) in a technical subject (e.g. life science, computing or mathematics)
  • 3+ years postgraduate experience in front-end software development with a demonstrable track record of delivery
  • Sound programming skills, including experience of Unix and Python
  • Experience in building and using web services and good knowledge of current web technologies;
  • Knowledge of search technologies e.g. Solr/Elastic
  • Knowledge of relational databases, SQL PL/SQL and NoSQL approaches
  • Evidence of good practice in software engineering to deliver clean, extensible and robust code through rapid development cycles with documentation and version control

For full details and to apply for the position, please visit the EMBL website:
https://www.embl.de/jobs/searchjobs/index.php?ref=EBI_01174&newlang=1&loc%5B%5D=2

Comments

Popular posts from this blog

ChEMBL 34 is out!

We are delighted to announce the release of ChEMBL 34, which includes a full update to drug and clinical candidate drug data. This version of the database, prepared on 28/03/2024 contains:         2,431,025 compounds (of which 2,409,270 have mol files)         3,106,257 compound records (non-unique compounds)         20,772,701 activities         1,644,390 assays         15,598 targets         89,892 documents Data can be downloaded from the ChEMBL FTP site:  https://ftp.ebi.ac.uk/pub/databases/chembl/ChEMBLdb/releases/chembl_34/ Please see ChEMBL_34 release notes for full details of all changes in this release:  https://ftp.ebi.ac.uk/pub/databases/chembl/ChEMBLdb/releases/chembl_34/chembl_34_release_notes.txt New Data Sources European Medicines Agency (src_id = 66): European Medicines Agency's data correspond to EMA drugs prior to 20 January 2023 (excluding ...

SureChEMBL gets a facelift

    Dear SureChEMBL users, Over the past year, we’ve introduced several updates to the SureChEMBL platform, focusing on improving functionality while maintaining a clean and intuitive design. Even small changes can have a big impact on your experience, and our goal remains the same: to provide high-quality patent annotation with a simple, effective way to find the data you need. What’s Changed? After careful consideration, we’ve redesigned the landing page to make your navigation smoother and more intuitive. From top to bottom: - Announcements Section: Stay up to date with the latest news and updates directly from this blog. Never miss any update! - Enhanced Search Bar: The main search bar is still your go-to for text searches, still with three pre-filter radio buttons to quickly narrow your results without hassle. - Improved Query Assistant: Our query assistant has been redesigned and upgraded to help you craft more precise queries. It now includes five operator options: E...

Here's a nice Christmas gift - ChEMBL 35 is out!

Use your well-deserved Christmas holidays to spend time with your loved ones and explore the new release of ChEMBL 35!            This fresh release comes with a wealth of new data sets and some new data sources as well. Examples include a total of 14 datasets deposited by by the ASAP ( AI-driven Structure-enabled Antiviral Platform) project, a new NTD data se t by Aberystwyth University on anti-schistosome activity, nine new chemical probe data sets, and seven new data sets for the Chemogenomic library of the EUbOPEN project. We also inlcuded a few new fields that do impr ove the provenance and FAIRness of the data we host in ChEMBL:  1) A CONTACT field has been added to the DOCs table which should contain a contact profile of someone willing to be contacted about details of the dataset (ideally an ORCID ID; up to 3 contacts can be provided). 2) In an effort to provide more detailed information about the source of a deposited dat...

Improvements in SureChEMBL's chemistry search and adoption of RDKit

    Dear SureChEMBL users, If you frequently rely on our "chemistry search" feature, today brings great news! We’ve recently implemented a major update that makes your search experience faster than ever. What's New? Last week, we upgraded our structure search engine by aligning it with the core code base used in ChEMBL . This update allows SureChEMBL to leverage our FPSim2 Python package , returning results in approximately one second. The similarity search relies on 256-bit RDKit -calculated ECFP4 fingerprints, and a single instance requires approximately 1 GB of RAM to run. SureChEMBL’s FPSim2 file is not currently available for download, but we are considering generating it periodicaly and have created it once for you to try in Google Colab ! For substructure searches, we now also use an RDKit -based solution via SubstructLibrary , which returns results several times faster than our previous implementation. Additionally, structure search results are now sorted by...

A python client for accessing ChEMBL web services

Motivation The CheMBL Web Services provide simple reliable programmatic access to the data stored in ChEMBL database. RESTful API approaches are quite easy to master in most languages but still require writing a few lines of code. Additionally, it can be a challenging task to write a nontrivial application using REST without any examples. These factors were the motivation for us to write a small client library for accessing web services from Python. Why Python? We choose this language because Python has become extremely popular (and still growing in use) in scientific applications; there are several Open Source chemical toolkits available in this language, and so the wealth of ChEMBL resources and functionality of those toolkits can be easily combined. Moreover, Python is a very web-friendly language and we wanted to show how easy complex resource acquisition can be expressed in Python. Reinventing the wheel? There are already some libraries providing access to ChEM...