I put together a graph this afternoon, from home, with no real network connection, no database access and a sick dog - so treat the rendering of the data as preliminary, but I think it is quite interesting. Anyway, below is a retrospective view of 2008 US drug approvals. 10 Orals, 13 Parenterals and 1 Topical. 2 Natural Product derived drugs (excluding peptide drugs). All is well with the Rule of Five. 6 with black-box warnings. 1 new target (but quite a few with unknown mode of action). 20 small molecules, and 4 peptide/protein drugs.....
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